The following list of cancer immunotherapies are available for licensing under U.S. Patent Publication No.: 20220306994.

Chimeric Cells Comprising Dendritic Cells and Endothelial Cells Resembling Tumor Endothelium

Abstract
 Disclosed are means, methods and compositions of matter useful for induction of immunological responses towards tumor endothelial cells. In one embodiment the invention teaches fusion of dendritic cells and cells resembling tumor endothelial cells and administration of such chimeric cells as an immunotherapy for stimulation of tumor endothelial cell destruction. In other embodiments pluripotent stem cells are utilized to generate dendritic cells, wherein said dendritic cells are fused with pluripotent stem cell derived endothelial cells created in a manner to resemble tumor endothelial cells.







Acinar cell carcinoma (ACC) is a rare pancreatic malignancy with distinctive clinical, molecular, and morphological features. The long-term survival of ACC patients is substantially superior to that of pancreatic adenocarcinoma patients.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Acinous carcinoma is a rare type of cancer that develops in the cells that produce mucus, called mucin. It can occur in many parts of the body, but is most common in the breast. Other common sites include the lungs, colon, or rectum.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Adenocystic carcinoma is a rare, slow-growing cancer that can develop in many parts of the body, but most often occurs in the salivary glands.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Adenoid cystic carcinoma is a rare, slow-growing cancer that can develop in many parts of the body, but most often occurs in the salivary glands.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma adenomatosum also known as adenocarcinoma, is a type of cancer that forms in the glandular tissue of internal organs. These glands produce substances like mucus and digestive juices. Adenocarcinoma is the most common type of cancer in organs, and can affect many areas of the body, including breast, colon or rectum, esophagus, lungs, pancreas, prostate, and stomach.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma of adrenal cortex is a rare, aggressive cancer that forms in the adrenal cortex, the outer layer of the adrenal glands.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Alveolar carcinoma, also known as bronchioloalveolar carcinoma (BAC) or terminal bronchiolar carcinoma, is a rare type of lung cancer that develops in the air sacs of the lungs.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Alveolar cell carcinoma also known as bronchioloalveolar carcinoma (BAC) or terminal bronchiolar carcinoma, is a rare type of lung cancer that develops in the air sacs of the lungs.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Basal cell carcinoma is a common type of skin cancer that develops when the DNA of basal cells in the skin’s epidermis is damaged. It’s also known as basal cell cancer, basalioma, or rodent ulcer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma basocellulare is a malignant skin cancer that originates in the basal cells of the skin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Basaloid carcinoma is a rare and aggressive type of cancer that can appear in the head and neck, lungs, or esophagus.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Basosquamous cell carcinoma is a rare, aggressive skin cancer that has features of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Bronchioalveolar carcinoma is a type of lung cancer that develops in the air sacs of the lungs. It’s a relatively uncommon type of non-small cell lung cancer (NSCLC), but it accounts for a growing proportion of adenocarcinomas.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Bronchiolar carcinoma is a type of lung cancer that develops in the small air sacs of the lungs. It’s a relatively rare and well-differentiated adenocarcinoma that typically grows along the alveolar walls without destroying the lung tissue.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Bronchogenic carcinoma, also known as lung cancer, is a malignant tumor that originates in the lungs’ airways or lung tissue. It is a leading cause of cancer-related deaths in the United States, and is responsible for more deaths in women than breast cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Cerebriform carcinoma nuclei are irregular and convoluted, and can appear in the upper dermis or in the paracortex of lymph nodes.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Cholangiocellular carcinoma is a rare, malignant tumor of the liver that originates in the cholangioles or canals of Hering.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Chorionic carcinoma is a rare, fast-growing, malignant tumor that develops from trophoblastic cells. These cells help the embryo attach to the uterus and form the placenta. Choriocarcinoma is also known as chorioblastoma or chorioepithelioma.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Colloid carcinoma, also known as mucinous carcinoma, is a rare type of cancer that produces a mucus-like substance. It can occur in several organs, including the breast, pancreas, and colon.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Comedo carcinoma is a kind of breast cancer that demonstrates comedonecrosis, which is the central necrosis of cancer cells within involved ducts.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Corpus carcinoma, also known as endometrial cancer, is a cancer that develops in the lining of the uterus and is the most common gynecological malignancy in the United States.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Cribriform carcinoma is a rare type of cancer that can occur in the breast, prostate, and colon.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma en cuirasse is a rare and aggressive form of metastatic breast cancer that appears as a thick, leathery covering on the chest wall, abdomen, and groin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma cutaneum is a term for skin cancer that can include cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC).

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Cylindrical carcinoma is a rare, malignant tumor that usually occurs in the sinuses and nasal cavity, but can also affect the nasopharynx and larynx.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Cylindrical cell carcinoma is a rare, malignant tumor that originates in the sinonasal respiratory epithelium. It’s also known as sinonasal non-keratinizing squamous cell carcinoma (SCC), transitional cell carcinoma, and other names. CCC is considered a low-grade malignancy that usually affects older patients.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Duct carcinoma is a type of breast cancer that begins in the milk ducts of the breast.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma durum is a type of cancer that starts in tissue lining your skin, organs and internal passageways in your body.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Embryonal carcinoma is a rare and aggressive type of cancer that can occur in the testicles or ovaries.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Encephaloid carcinoma is a type of invasive breast cancer that starts in the milk ducts. It’s a rare cancer that’s less than 5% of all invasive breast cancers. Despite its aggressive nature, it often has a better prognosis than other types of invasive breast cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Epidermoid carcinoma also known as squamous cell carcinoma (SCC), is a type of cancer that starts in squamous cells.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma epithelial adenoids is a rare type of cancer that develops in the glandular tissues of the body, including the salivary glands, and is characterized by abnormal epithelial cells.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Exophytic carcinoma grow out from the mucosal surface in cauliflower-like clusters, and rapidly become symptomatic.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma ex ulcere, also known as ulcer-cancer of the stomach, is a type of cancer that can develop in the stomach. There is a positive association between gastric ulcers and the development of gastric cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma fibrosum, also known as fibrosarcoma, is a rare and aggressive type of soft tissue cancer that affects the body’s connective tissues.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Gelatiniform carcinoma, also known as colloid carcinoma or mucoid carcinoma, is a type of cancer that can affect the breast.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Gelatinous carcinoma, also known as mucinous carcinoma, is a rare and poorly understood cancer that produces a jelly-like substance called mucin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Giant cell carcinoma is a rare type of large-cell lung carcinoma, a subtype of undifferentiated lung cancer. Giant cell tumors (GCTs) are a different type of tumor that can occur in bones, cartilage, muscle, fat, blood vessels, and other tissues.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Signet-ring cell carcinoma is a rare, aggressive, and fast-growing type of cancer that forms in glandular cells. It’s named for the cells’ appearance under a microscope, which resembles a signet ring. SRCC can develop in many parts of the body, but it most commonly starts in the stomach or gastrointestinal (GI) tract.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma simplex is a malignant epithelial neoplasm that is undifferentiated and tends to spread to other parts of the body and infiltrate surrounding tissues.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Small-cell carcinoma is a fast-growing, aggressive type of lung cancer that can spread to other parts of the body.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Solanoid carcinoma

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Spheroidal cell carcinoma is a spherical mass of cancer cells with a diameter of approximately 400 μm, which contains tens of thousands of cells.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Spindle cell carcinoma is a rare and aggressive cancer that can occur in the skin or in the tissues that line organs. It’s characterized by long, spindle-shaped cells that resemble malignant fibroblasts.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma spongiosum is a term used in the American Joint Committee on Cancer’s (AJCC) tumor-node-metastasis (TNM) staging system for penile cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Squamous carcinoma, also known as squamous cell carcinoma, is a type of cancer that can occur in the skin, respiratory and digestive tracts, and the lining of hollow organs. It’s caused by exposure to ultraviolet (UV) radiation from the sun or tanning beds.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Squamous cell carcinoma is a type of cancer that can develop in the skin, the lining of hollow organs, or the lining of the respiratory and digestive tracts. It’s the second most common type of skin cancer in the United States.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

String carcinoma is a type of cancer that forms in epithelial tissue, which lines the skin, organs, and internal passageways of the body.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma telangiectaticum, also known as telangiectatic metastatic breast carcinoma (TMBC), is a rare type of breast cancer that spreads to the skin

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma telangiectodes is a rare form of cutaneous carcinoma metastases.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Transitional cell carcinoma is a type of cancer that starts in the transitional cells, or urothelium, that line the urinary tract.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma tuberosum Inhibits the growth of Ehrlich ascites carcinoma cells by causing apoptosis and G2/M cell cycle arrest.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Tuberous carcinoma is a rare and slow-growing type of breast cancer that’s characterized by its tube-like structures. It’s a subtype of invasive ductal carcinoma (IDC) and usually starts in the milk duct of the breast.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Verrmcous carcinoma is a low-grade variant of squamous cell carcinoma with specific morphologic, cytokinetic and clinical features. Despite low mitotic activity and slow growth, it can infiltrate adjacent tissues in advanced stages but does not metastasize. The most frequently affected site is the oral cavity..

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma villosum are a type of tumor that can have a malignant risk of 15–25%. The risk of developing adenocarcinoma is higher in villous adenomas that are larger than 4 cm in diameter, with a risk of almost 40%.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma gigantocellulare is a rare and highly aggressive type of lung cancer that’s characterized by large, bizarre tumor cells.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Glandular carcinoma is a type of cancer that develops in glandular tissue, which lines many internal organs.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Granulosa cell carcinoma is a rare, slow-growing, malignant ovarian tumor that accounts for about 5% of all ovarian cancers. GCTs are known for their hormonal activity, and can secrete estrogen, inhibin, and Mullerian inhibiting substance.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hair-matrix carcinoma also known as pilomatrix carcinoma, is a rare, malignant tumor that develops from the hair matrix.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hematoid carcinoma, a rare and easily misdiagnosed type of gastric cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hepatocellular carcinoma, also known as liver cancer, is a primary liver tumor that is the most common type of liver cancer in adults.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hurthle cell carcinoma is a rare and aggressive type of thyroid cancer that can cause tumors that affect breathing and speaking.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hyaline carcinoma is an extremely rare neoplasm with a female predominance, composed of nests of monomorphic clear cells within a hyaline stroma. This tumor often follows an indolent course and treatment includes wide surgical excision with or without adjuvant radiotherapy.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Hypemephroid carcinoma, also known as clear-cell adenocarcinoma, is the most common kidney tumor in adults. It can spread into the inferior vena cava and is more likely to do so than other tumors.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Infantile embryonal carcinoma, also known as endodermal sinus tumor, is a rare, malignant germ cell tumor that occurs in the testicles of children under three years old.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma in situ is a group of abnormal cells that are only found in the place where they first formed in the body. It’s also known as stage 0 cancer, noninvasive cancer, or preinvasive cancer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Intraepidermal carcinoma, also known as squamous cell carcinoma in situ (SCCIS) or Bowen disease, is a non-invasive skin cancer that occurs when cancerous cells develop and remain in the epidermis, the skin’s outermost layer.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Intraepithelial carcinoma is a lesion that occurs when malignant cells replace the surface epithelium or glands of an organ.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Krompecher carcinoma is another name for basal cell carcinoma (BCC), a type of skin cancer that was first described by Edmund Krompecher in 1903.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Kulchitzky-cell carcinoma is a term for neuroendocrine carcinomas of the lung that differentiate toward Kulchitsky cells. Kulchitsky cells, also known as enterochromaffin cells, are neuroendocrine cells that are thought to be the origin of small cell lung cancer (SCLC).

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Large-cell carcinoma is a type of lung cancer that’s made up of large, undifferentiated cancer cells that grow and spread quickly.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Lenticular carcinoma is an early form of melanoma in which the malignant cells are confined to the tissue of origin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma lenticulare is a type of cancer that initially appears as small, flat, pea-sized nodules or papules.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Lipomatous carcinoma is a term that refers to a range of tumors that can be benign or malignant, including lipomas, atypical lipomatous tumors (ALTs), and liposarcomas.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Lymphoepithelial carcinoma is a rare, inflammatory type of squamous cell carcinoma that can occur in several tissues, including the throat, salivary glands, and skin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma medullare is a rare type of thyroid cancer that starts in the cells of the thyroid gland that produce calcitonin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Medullary carcinoma is a rare type of thyroid cancer that starts in the cells of the thyroid gland that produce calcitonin.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Melanotic carcinoma tumors are derived from melanocytes. These cells migrate during embryogenesis and populate the skin as well as mucosal surfaces.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma molle is a type of cancer that starts in the cells that line or cover an organ.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Mucinous carcinoma is a rare type of cancer that develops in the cells that produce mucus, called mucin. It can occur in many parts of the body, but is most common in the breast. Other common sites include the lungs, colon, or rectum.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma muciparum, also known as mucinous adenocarcinoma or colloid carcinoma, is a rare type of cancer that occurs when cancer cells form in mucin, the main component of mucus.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma mucocellulare s a metastatic ovarian cancer that originates from primary tumors in other parts of the body.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Mucoepidermoid carcinoma is a rare type of cancer that can affect the salivary glands, lungs, and other organs

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma mucosum is a type of cancer that develops in the lining of the mouth.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Mucous carcinoma is a rare type of cancer that develops in the cells that produce mucus, called mucin. It can occur in many parts of the body, but is most common in the breast. Other common sites include the lungs, colon, or rectum.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma myxomatodes of the testis originating in the intratesticular ducts.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Naspharyngeal carcinoma is cancer that happens in the nasopharynx, which sits behind the nose and above the back of the throat.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Oat cell carcinoma , also known as small cell carcinoma, is a type of lung cancer that grows and spreads quickly and is usually caused by smoking.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma ossificans is a type of cancer that can begin in the skin or tissues that line or cover internal organs.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Osteoid carcinoma is a benign bone-forming tumor that has no potential to become malignant. It classically causes severe pain at night relieved with nonsteroidal anti-inflammatory medications. Occasionally, it resolves without treatment. If it is painful, initial treatment consists of anti-inflammatory medications.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Papillary carcinoma is the most common type of thyroid cancer, accounting for about 80–90% of all thyroid cancers. It’s usually slow-growing and has a good prognosis, especially for patients under 45.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Periportal carcinoma is a cancer that occurs in the periportal space, the area around the portal vein and its branches in the liver.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Preinvasive carcinoma, also known as carcinoma in situ, is a stage of cancer development where the cancer cells are still contained within the walls of an organ and have not yet spread into the surrounding tissue. Preinvasive carcinoma is a stage that indicates the cancer will eventually develop into an invasive form.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Prickle cell carcinoma is a type of skin cancer that can appear as a firm bump, scaly patch, open sore, or wart.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Pultaceous carcinoma is a type of pleural cancer that occurs in the pleural cavity, which is the space outside the lungs in the chest. It usually spreads to the pleura from another part of the body.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Renal cell carcinoma of kidney is the most common type of kidney cancer. Other, less common types of kidney cancer can happen.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Reserve cell carcinoma s another name for small cell carcinoma, a type of tumor that can originate in the lungs or other parts of the body. Small cell carcinoma can also be called oat cell carcinoma, sarcoma, or other names.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma sarcomatodes is a rare, aggressive cancer that’s a combination of carcinoma and sarcoma.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Schneiderian carcinoma is a rare and aggressive cancer that can develop in the Schneiderian epithelium, the lining of the nose and paranasal sinuses.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Scirrhous carcinoma is a rare, slow-growing, and hard cancer that can occur in the breast, stomach, colon, and oral cavity.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%

Carcinoma scroti is a rare cancer that can affect the scrotum and is most commonly caused by squamous cell carcinoma.

Upfront Fee Annual Minimum Royalty Phase 1 IND Phase 2 IND Phase 3 IND BLA Royalty
$50,000 $10,000 $100,000 $250,000 $500,000 $1,000,000 6%